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EPIDEMICS
Litmus strip-like Ebola diagnostic test works in 30 minutes
by Brooks Hays
Boston (UPI) Oct 27, 2014


Mobile app helps track Ebola epidemic
Nairobi (AFP) Oct 27, 2014 - A new mobile telephone based mapping service has been created in a bid to track Ebola and better help communities hit by the virus in west Africa, developers said Monday.

The system, a collaboration between technology giant IBM, mobile telephone companies and academics, allows people in affected areas to send free text messages about Ebola to track problems and trends, with the program mapping the exact location from where it is sent.

"It has already brought to light specific regions with growing numbers of suspected Ebola cases which require urgent supplies like soap and electricity, as well as faster response times for body collection and burials," IBM said.

The company claims it can create a range of maps to track needs and problems, to better allow health workers and governments tackle them.

"We saw the need to quickly develop a system to enable communities directly affected by Ebola to provide valuable insight about how to fight it," IBM Research Africa's chief scientist Uyi Stewart said in a statement.

"Using mobile technology, we have given them a voice and a channel to communicate their experiences directly," Stewart said.

More than 10,000 people have contracted the deadly virus in west Africa, according to the latest World Health Organization figures.

A team of synthetic biologists have developed a prototype paper test that they say can detect the presence of Ebola strains within 30 minutes, a development that could make the process of finding and containing the disease faster and more efficient.

The litmus-like test utilizes a technology that's popular in science labs called "cell free system," whereby cellular processes are replicated and observed in a test tube. To create the new Ebola test, researchers installed the cell free system on a strip of porous paper.

The amalgamation of biological ingredients is freeze dried on the paper and reacts when presented with a strain of Ebola. Researchers say the technology could be adapted for all kinds of disease detection. A new sort of genetic soup can be programmed to react and respond to a range of biochemical inputs.

"In a period of just 12 hours, two of my team managed to develop 24 sensors that would detect different regions of the Ebola genome, and discriminate between the Sudan and the Zaire strains," Jim Collins, a synthetic biologist at Boston University who lead the team of researchers, told BBC News.

"It's a pragmatic, very big-deal improvement," Julius Lucks, a chemical engineer at Cornell University, told the MIT Technology Review. "Now we can ask 'What do we want to do [with it]?'"

Collins and his colleagues admit that the test still requires some level of lab expertise, so they don't think the technology is quite ready for the epidemic centers of West Africa; but they say they're not far from developing one that is.

Their research was detailed last week in the latest issue of the scientific journal Cell.


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EPIDEMICS
US troops quarantined in Italy after W. Africa stint
Washington (AFP) Oct 27, 2014
US troops returning from West Africa are being quarantined at a base in Italy as a precaution to prevent the potential spread of the Ebola virus, the Pentagon said Monday. The outgoing commander of the US military mission in Liberia, Major General Darryl Williams, along with 11 other members of his staff, were the first to undergo the isolation measures, which will last up to 21 days, a Pent ... read more


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