Iranian President Hassan Rouhani on Monday warned his American counterpart Donald Trump to "never threaten the Iranian nation", after he issued a US strike list of 52 targets in the Islamic republic.

"Those who refer to the number 52 should also remember the number 290. #IR655 Never threaten the Iranian nation," he tweeted, referring to 290 lives lost in July 1988 when a US warship shot down passenger plane Iran Air 655 in the Gulf.

Trump warned Saturday that Washington had lined up 52 targets in Iran if it attacked American personnel or assets in retaliation for a US drone strike in Baghdad that killed Iran's top commander Qasem Soleimani.

He said 52 represented the number of Americans held hostage at the US embassy in Tehran for more than a year starting in late 1979.

Trump said some of these sites are "at a very high level & important to Iran & the Iranian culture, and those targets, and Iran itself, WILL BE HIT VERY FAST AND VERY HARD."

Later, the president tweeted again, this time warning Iran that the US will hit Iran "harder than they have ever been hit before!"

NATO tells Iran to avoid 'further provocations'
Brussels (AFP) Jan 6, 2020 - Tehran should avoid "further violence and provocations", NATO chief Jens Stoltenberg warned Monday, as tensions mount in the Middle East after US forces killed a top Iranian general.

The warning came as the EU called an extraordinary meeting of foreign ministers in Brussels on Friday to discuss the fallout from the killing of Qasem Soleimani, head of Tehran's Middle East operations as commander of the Revolutionary Guards' Quds Force.

At a hastily-convened emergency session of NATO's ruling council on Monday afternoon, US officials explained the thinking behind the decision to kill Soleimani at Baghdad airport on Friday -- an operation that caught many of Washington's allies by surprise.

Stoltenberg stressed that the drone strike, which killed at least 10 people, was a "US decision" but said the other 28 NATO members had repeated their longstanding concerns about Iran's destabilising activities in the Middle East.

Asked twice whether any member states criticised the US strike, Stoltenberg stressed their unity and their concern about Iran's behaviour.

"We have recently seen an escalation by Iran, including the strike on a Saudi energy facility, and the shoot-down of an American drone," Stoltenberg said.

"At our meeting today, Allies called for restraint and de-escalation. A new conflict would be in no-one's interest, so Iran must refrain from further violence and provocations."

Tehran has vowed to avenge Soleimani, one of Iran's most popular public figures and a key player in its network of alliances and proxy forces around the Middle East, while US President Donald Trump has threatened "major retaliation" if any American targets are hit.

European Commission President Ursula von der Leyen said the EU was talking to all parties to try to defuse tensions, calling for restraint and urging gains made in Iraq since the defeat of the Islamic State group to be preserved.

"After recent developments in Iraq, now it is important to halt the cycle of violence so that one more action does not give rise to the next one, and instead space is again created for diplomacy," von der Leyen said.

Friday's meeting of foreign ministers will also address the 2015 nuclear deal with Tehran, which curbed its nuclear programme in return for sanctions relief but is now teetering on the brink of collapse.

EU diplomatic chief Josep Borrell tweeted that the accord, which has been unravelling since US President Donald Trump pulled out in May 2018, was "now more important than ever".

And he criticised Tehran's latest steps away from the accord, after it said it would forego the "limit on the number of centrifuges", casting doubt on an EU push for talks to salvage the deal.

Borrell spoke to Iranian Foreign Minister Mohammed Javad Zarif at the weekend and issued a personal invitation to come to Brussels, but so far Iran has not given a public response.

- Training mission suspended -

At Monday's NATO meeting the US "provided the rationale behind the action against General Soleimani", Stoltenberg said but refused to give further details.

The situation has also deteriorated in Iraq, where lawmakers have called for the 5,200 US soldiers deployed there to leave.

NATO maintains a 500-strong mission in Iraq, preparing local forces to take on Islamic State group extremists, but its core training activities have now been suspended until the security situation improves, Stoltenberg said.

A NATO diplomat told AFP the alliance would have to "wait and see" how Baghdad responds in the coming days.

"From our point of view the parliament resolution is not binding. We take note of it, but have to wait what the government is going to do," the diplomat said.

"We still think that the presence of international troops in Iraq should be continued in order to prevent a resurgence of Islamic State. But we have to respect what the Iraqi government will eventually decide."

Britain, France and Germany issued a joint statement late on Sunday urging Iran to "refrain from further violent action or proliferation" and criticising the "negative role" Tehran played in the Middle East through Soleimani's forces.

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Mourners pack Tehran to grieve Iran general Soleimani
Tehran (AFP) Jan 6, 2020
Mourners packed the streets of Tehran on Monday for ceremonies to pay homage to top Iranian military commander Qasem Soleimani, after he was killed in a US strike in Baghdad. Clutching portraits of their hero, the crowd gathered on the outskirts of Tehran University where the supreme leader is to preside over prayers for the slain general, an AFP correspondent reported. In freezing early morning temperatures, women in black walked alongside men holding up flags bearing the names of Shiite imams ... read more