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EPIDEMICS
US researchers develop new tool in HIV vaccine fight
by Staff Writers
Washington (AFP) May 9, 2013


US researchers have developed a new test to identify antibodies capable of fighting most strains of HIV, the virus that causes AIDS, in a breakthrough that could accelerate the hunt for a vaccine.

A report published in the journal Science on Thursday said that scientists at the National Institute of Allergy and Infectious Diseases had studied HIV-infected individuals whose blood had shown "powerful neutralization" qualities of the virus.

The new tool allowed scientists to precisely determine the broadly neutralizing antibodies in a given sample by analyzing the neutralized HIV strains.

The tool -- known as neutralization fingerprinting -- is a mathematical algorithm that taps into the large pool of data on HIV bNAbs (broadly neutralizing antibodies) generated in recent years.

The neutralization fingerprint of an HIV antibody allows scientists to determine which strains of the virus it can block and how effectively it does so.

Previous techniques to yield the same information were far slower and "extremely laborious," the study said.

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Related Links
Epidemics on Earth - Bird Flu, HIV/AIDS, Ebola






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EPIDEMICS
New insights into Ebola infection pave the way for much-needed therapies
London, UK (SPX) May 10, 2013
The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in the Biophysical Journal reveals how the most abundant protein making up the Ebola virus-viral protein 40 (VP40)-allows the virus to leave host cells and spread infection to other cells thr ... read more


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